Safren SA, O’Cleirigh C, Skeer M, Driskell J, Goshe BM, Covahey C, Mayer KH.I have led and co-lead trials both domestically and internationally, with studies that address syndemic indicators that lay the context for poor health behaviors. This work has included behavioral interventions to reduce sexual acquisition and transmission risk among men who have sex with men. In press.Ģ. Primary and secondary behavioral HIV prevention interventions for in men who have sex with men (MSM): domestic and global work, including stepped care interventions. Journal of the International AIDS Society, JIAS. Treating depression and improving adherence in HIV care with task-shifted cognitive-behavioral therapy in Khayelitsha, South Africa: A randomized controlled trial. Safren SA, O’Cleirigh C, Andersen LS, Magidson, JF, Lee JS, Bainter SA, Musinguzi N., Simoni J, Kagee A., Joska JA.Treating Depression and Adherence (CBT-AD) in Patients with HIV in Care: A Three-arm Randomized Controlled Trial. Safren SA, Bedoya CA, O'Cleirigh C, Biello KB, Pinkston MM, Stein MD, Traeger L, Kojic E, Robbins GK, Lerner JA, Herman DS, Mimiaga MJ, & Mayer KH.Journal of Consulting and Clinical Psychology, 80, 404-415.
Cognitive Behavioral Therapy for Adherence and Depression (CBT-AD) in HIV-infected Injection Drug Users: A Randomized Controlled Trial. Safren SA, O’Cleirigh CM, Bullis JR, Otto MS, Stein MD, Pollack MH.Behavioural Research and Therapy, 39, 1151-1162. (2001).Two strategies to increase adherence to HIV antiretroviral medication: Life-Steps and medication monitoring. Safren SA, Otto, MW, Worth J, Salomon E.Africa which showed effects on viral load and depression/adherence outcomes.
SAS UNIVERSITY EDITION ONLY HAVE 32 TRIAL
I recently completed a an R01 of a nurse-delivered effectiveness trial of this intervention in collaboration with the University of Cape Town in S. Mexico Border via an R34 lead by Jane Simoni and a tele-medicine approach for African American women with HIV living in the Deep South lead by Mirjam Kempf. I have conducted several funded trials of this approach examining this approach and it has been picked up by others being extended to a Spanish version at the U.S. This was an internet-based pager system.įrom these two trials, co-occurring behavioral health problems were prevalent and related to outcomes, so I began working on cognitive behavioral therapy for adherence and depression (CBT-AD) which integrated my approach to adherence counseling with general approaches to treating depression, psychosocially, in individuals with medical illness. Shortly thereafter, I completed a second RCT of an adherence intervention, which addressed the frequently identified problem of “forgetting” to take one’s medications. I developed and tested the first randomized controlled trial (RCT) of an adherence to ART treatment intervention, called “Life-Steps” using a cognitive-behavioral which is now used all over the world, including by MSF treatment clinics in S.
Adherence to antiretroviral therapy for HIV treatment, developing the Life-Steps approach. Please see below for 5 topical areas of research that I study, followed by a list of selected current funded projects that I lead or co-lead.ġ. I am also the Co-Director of the Behavioral/Social Sciences and Community Outreach Core for the UM Center for AIDS Research (CFAR). Finally, I developed and tested one of the only evidenced-based psychosocial treatments for ADHD in adults, and extended that to adolescents. I have been PI or protocol chair of 18 federally funded studies (via NIMH, NIDA, and NIAID), and, in addition to studies where I am PI, I have regularly served as co-PI, co-investigator, or mentor on studies related to HIV prevention and treatment. I joined the Department of Psychology at the University in of Miami in 2015 after 18 years working in the Harvard Medical School system at Massachusetts General Hospital where I was a Professor and Director of the Behavioral Medicine Service, and led behavioral science studies at Fenway Health. Within HIV prevention, many of my projects investigate social, contextual, and behavioral health issues related to sexual and gender minority populations. For example, I have developed and tested adherence and combined depression/adherence interventions that are being used globally. I am the Director of the UM Center for HIV and Research in Mental Health (NIMH-funded Developmental AIDS Research Center D-ARC) and the Health Promotion and Care research program ( ) where we study health behavior change, with a particular emphasis on mental health and substance use components of HIV prevention and treatment domestically and internationally.